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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
8
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pubmed:dateCreated |
2001-3-6
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|
pubmed:abstractText |
Expression of the VLDL receptor, primarily in macrophages, has been confirmed in human and rabbit atherosclerotic lesions. The high binding affinity of the VLDL receptor for remnant particles implicates the VLDL receptor pathway in the foam cell formation mechanism in macrophages. This study investigates the effect of interferon (IFN)-gamma on VLDL receptor expression in phorbol-12-myristate-13-acetate (PMA)-treated THP-1, HL-60 macrophages, and human monocyte-derived macrophages.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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|
pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:HattoriHH,
pubmed-author:IwasakiTT,
pubmed-author:KaneharaHH,
pubmed-author:KodamaTT,
pubmed-author:KosakaSS,
pubmed-author:MasamuraKK,
pubmed-author:MiyamoriII,
pubmed-author:OidaKK,
pubmed-author:OkadaEE,
pubmed-author:SakaiJJ,
pubmed-author:TakahashiSS,
pubmed-author:TohdaGG,
pubmed-author:YamamotoTT
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pubmed:issnType |
Electronic
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pubmed:day |
27
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pubmed:volume |
103
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1142-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11222479-Cell Differentiation,
pubmed-meshheading:11222479-Foam Cells,
pubmed-meshheading:11222479-Gene Expression,
pubmed-meshheading:11222479-HL-60 Cells,
pubmed-meshheading:11222479-Heymann Nephritis Antigenic Complex,
pubmed-meshheading:11222479-Humans,
pubmed-meshheading:11222479-Interferon-gamma,
pubmed-meshheading:11222479-Macrophages,
pubmed-meshheading:11222479-Membrane Glycoproteins,
pubmed-meshheading:11222479-Monocytes,
pubmed-meshheading:11222479-Receptors, LDL,
pubmed-meshheading:11222479-Tumor Cells, Cultured
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pubmed:year |
2001
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pubmed:articleTitle |
Evidence of macrophage foam cell formation by very low-density lipoprotein receptor: interferon-gamma inhibition of very low-density lipoprotein receptor expression and foam cell formation in macrophages.
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pubmed:affiliation |
Third Department of Internal Medicine, Fukui Medical University, Fukui, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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