Linked Life Data

11220988

Source:http://linkedlifedata.com/resource/pubmed/id/11220988

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2001-2-26
pubmed:abstractText
This article is a review of the development of male steroidal contraceptives during the past 25 years. Numerous studies have been conducted on male volunteers with oral and/or injectable preparations of single or combined steroids. Progestogen, androgen alone, or progestogen and androgen combinations have been used as weekly or monthly injectable formulations. Most of the studies involved small numbers of subjects. There was reversible suppression of spermatogenesis to oligospermia and/or azoospermia during the treatment period. Alteration of LH, FSH and testosterone levels in the blood was observed in most of these studies, depending on the steroid or combination of steroids used. There were reports about decreased or increased libido and weight gain during treatment with steroids. No other serious side-effects were found. Attention has recently focused on developing an androgen-only male contraceptive, because testosterone ester has shown promising results. The development of an effective and reliable steroidal contraceptive for men may be possible but this requires further research.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1368-5031
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
594-603
pubmed:dateRevised
2007-2-14
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Steroidal contraception for men.
pubmed:affiliation
Department of Reproductive Biology, All India Institute of Medical Sciences, Ansarinagar, New Delhi 110 029, India.
pubmed:publicationType
Journal Article, Review