Linked Life Data

11216519

Source:http://linkedlifedata.com/resource/pubmed/id/11216519

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-2-16
pubmed:abstractText
64Cu (half-life, 12.7 h; beta+, 0.653 MeV [17.4%]; beta-, 0.579 MeV [39%]) has shown potential as a radioisotope for PET imaging and radiotherapy. (111)In-diethylenetriaminepentaacetic acid (DTPA)-D-Phe1-octreotide (OC) was developed for imaging somatostatin-receptor-positive tumors using conventional scintigraphy. With the advantages of PET over conventional scintigraphy, an agent for PET imaging of these tumors is desirable. Here, we show that 64Cu-TETA-OC (where TETA is 1,4,8,11-tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic acid) and PET can be used to detect somatostatin-receptor-positive tumors in humans.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0161-5505
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
213-21
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:11216519-Adenoma, Islet Cell, pubmed-meshheading:11216519-Aged, pubmed-meshheading:11216519-Animals, pubmed-meshheading:11216519-Carcinoid Tumor, pubmed-meshheading:11216519-Female, pubmed-meshheading:11216519-Gastrointestinal Neoplasms, pubmed-meshheading:11216519-Humans, pubmed-meshheading:11216519-Indium Radioisotopes, pubmed-meshheading:11216519-Male, pubmed-meshheading:11216519-Middle Aged, pubmed-meshheading:11216519-Neuroendocrine Tumors, pubmed-meshheading:11216519-Octreotide, pubmed-meshheading:11216519-Organometallic Compounds, pubmed-meshheading:11216519-Pancreatic Neoplasms, pubmed-meshheading:11216519-Papio, pubmed-meshheading:11216519-Pentetic Acid, pubmed-meshheading:11216519-Radiation Dosage, pubmed-meshheading:11216519-Radiopharmaceuticals, pubmed-meshheading:11216519-Receptors, Somatostatin, pubmed-meshheading:11216519-Sensitivity and Specificity, pubmed-meshheading:11216519-Tomography, Emission-Computed
pubmed:year
2001
pubmed:articleTitle
64Cu-TETA-octreotide as a PET imaging agent for patients with neuroendocrine tumors.
pubmed:affiliation
Mallinckrodt Institute of Radiology, Washington University School of Medicine. St. Louis, Missouri 63110, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't