Source:http://linkedlifedata.com/resource/pubmed/id/11214777
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9-10
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pubmed:dateCreated |
2001-2-14
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pubmed:abstractText |
The acetylation polymorphism is a common inherited variation in human drug and carcinogen metabolism. Because N-acetyltransferase (NAT2) is important for the detoxification and/or bioactivation of drugs and carcinogens, this polymorphism has important implications in therapeutics and cancer susceptibility. A high correlation between acetylation phenotype and genotype has been demonstrated in several studies. However, no such data exist for Chinese females. The aim of the present study was to compare acetylation phenotype with NAT2 genotype in a population of primarily non-smoking Chinese females.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0031-6970
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
689-92
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11214777-Acetylation,
pubmed-meshheading:11214777-Adult,
pubmed-meshheading:11214777-Aged,
pubmed-meshheading:11214777-Aged, 80 and over,
pubmed-meshheading:11214777-Arylamine N-Acetyltransferase,
pubmed-meshheading:11214777-Caffeine,
pubmed-meshheading:11214777-China,
pubmed-meshheading:11214777-Female,
pubmed-meshheading:11214777-Genotype,
pubmed-meshheading:11214777-Humans,
pubmed-meshheading:11214777-Middle Aged,
pubmed-meshheading:11214777-Phenotype,
pubmed-meshheading:11214777-Phosphoric Diester Hydrolases,
pubmed-meshheading:11214777-Polymorphism, Genetic,
pubmed-meshheading:11214777-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2000
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pubmed:articleTitle |
Correlation between acetylation phenotype and genotype in Chinese women.
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pubmed:affiliation |
Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore, Republic of Singapore. cofzhaob@nus.edu.sg
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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