Linked Life Data

11212222

Source:http://linkedlifedata.com/resource/pubmed/id/11212222

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2001-2-9
pubmed:abstractText
Alveolar gas transfer over a given breath (i) was determined in ten subjects at rest and during steady-state cycling at 60, 90 or 120 W as the sum of volume of gas transferred at the mouth plus the changes of the alveolar gas stores. This is given by the gas fraction (FA) change at constant volume plus the volume change (deltaVAi) at constant fraction i.e. VAi-1(FAi-FAi-1)+FAi x deltaVAi, where VAi-1 is the end-expiratory volume at the beginning of the breath. These quantities, except for VAi-1, can be measured on a single-breath (breath-by-breath) basis and VAi-1 set equal to the subject's functional residual capacity (FRC, Auchincloss model). Alternatively, the respiratory cycle can be defined as the interval elapsing between two equal expiratory gas fractions in two successive breaths (Grønlund model G). In this case, Ft1 = Ft2 and thus the term VAi-1 (FAi-FAi-1) vanishes. In the present study, average alveolar O2 uptake (VO2,A) and CO2 output (VCO2,A) were equal in both approaches whereby the mean signal-to-noise ratio (S/N) was 40% larger in G. Other approaches yield steady state S/N values equal to that obtained in G, although they are based on the questionable assumption that the inter-breath variability of alveolar gas transfer is minimal. It is concluded that the only promising approach for assessing "true" single-breath alveolar gas transfer is that originally proposed by Grønlund.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0031-6768
pubmed:author
pubmed:issnType
Print
pubmed:volume
441
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
566-77
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
New perspectives in breath-by-breath determination of alveolar gas exchange in humans.
pubmed:affiliation
Dipartimento di Scienze e Tecnologie Biomediche, School of Medicine, Udine, Italy. ccapelli@makek.dstb.uniud.it
pubmed:publicationType
Journal Article