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pubmed-article:11212112pubmed:abstractTextNovel rigidified (R)-aporphine derivatives were synthesized from (R)-1,11-carbonylaporphine by ring expansion reactions. The structures of the novel analogues were assigned by NMR spectroscopy and X-ray crystallography. The compounds showed moderate affinities and selectivities at serotonin S-HT1A and 5-HT7 and dopamine D2A receptors.lld:pubmed
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pubmed-article:11212112pubmed:articleTitleSerotonergic and dopaminergic activities of rigidified (R)-aporphine derivatives.lld:pubmed
pubmed-article:11212112pubmed:affiliationOrganic Pharmaceutical Chemistry, Uppsala University, Uppsala Biomedical Center, Sweden.lld:pubmed
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