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rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0019171,
umls-concept:C0205216,
umls-concept:C0209738,
umls-concept:C0332281,
umls-concept:C0596988,
umls-concept:C0598312,
umls-concept:C0683598,
umls-concept:C1335440,
umls-concept:C1515655,
umls-concept:C1516240,
umls-concept:C1533691,
umls-concept:C1718813
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pubmed:issue |
1
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pubmed:dateCreated |
2001-2-9
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pubmed:abstractText |
Hepatitis B virus mutants of the polymerase gene are frequently selected during lamivudine therapy for chronic hepatitis B. To study the biology of these mutants, we analyzed their replication capacity in the duck hepatitis B virus (DHBV) infection.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0168-8278
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
114-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11211887-Adenine,
pubmed-meshheading:11211887-Amino Acid Sequence,
pubmed-meshheading:11211887-Antiviral Agents,
pubmed-meshheading:11211887-DNA, Viral,
pubmed-meshheading:11211887-Drug Resistance,
pubmed-meshheading:11211887-Hepatitis B Virus, Duck,
pubmed-meshheading:11211887-Lamivudine,
pubmed-meshheading:11211887-Molecular Sequence Data,
pubmed-meshheading:11211887-Mutation,
pubmed-meshheading:11211887-Phosphonic Acids,
pubmed-meshheading:11211887-RNA-Directed DNA Polymerase,
pubmed-meshheading:11211887-Transcription, Genetic
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pubmed:year |
2001
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pubmed:articleTitle |
Duck hepatitis B virus polymerase gene mutants associated with resistance to lamivudine have a decreased replication capacity in vitro and in vivo.
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pubmed:affiliation |
INSERM Unit 271, Lyon, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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