Linked Life Data

1121054

Source:http://linkedlifedata.com/resource/pubmed/id/1121054

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1975-6-26
pubmed:abstractText
With 7 repeated measurements of the mean circulatory pressure (MCP) over a course of 35 minutes in one and the same dog, and also with paired measurements of MCP 10 minutes apart in 6 other dogs, the MCP was shown to be stable and reproducible in anesthetized, open-chest and vagus-intact dogs. Administered to 7 dogs with initial mean arterial blood pressure as low as 64 mmHg in dose of 20 mug/kg intravenously, phenylephrine nearly doubled the mean arterial blood pressure, total peripheral resistance and the MCP, indicating a marked vasoconstrictor effect on the resistance and capacitance blood vessels of the systemic circulation. The effect was transient and there were signs of tachyphylaxis. Influence of a cardiotoxic dose of pentobarbital on the peripheal circulation was discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0047-1828
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
403-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
The mean circulatory pressure, reproducibility of its measurements and the effect of phenylephrine with a note on the effect of pentobarbital.
pubmed:publicationType
Journal Article