Source:http://linkedlifedata.com/resource/pubmed/id/11209133
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2001-3-21
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pubmed:abstractText |
Transgenic mice overexpressing hepatocyte growth factor/scatter factor (HGF/SF) demonstrate extensive pigmented nevi in both skin and leptomeninges of the central nervous system resembling human neurocutaneous melanosis. We immunohistochemically detected HGF/SF receptor, Met, in a congenital nevus of an infant with neurocutaneous melanosis, indicating that deregulation of HGF/SF-Met signaling in the critical period of development may lead to this fatal syndrome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0190-9622
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
538-40
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11209133-Animals,
pubmed-meshheading:11209133-Child, Preschool,
pubmed-meshheading:11209133-Humans,
pubmed-meshheading:11209133-Immunohistochemistry,
pubmed-meshheading:11209133-Male,
pubmed-meshheading:11209133-Melanosis,
pubmed-meshheading:11209133-Mice,
pubmed-meshheading:11209133-Neurocutaneous Syndromes,
pubmed-meshheading:11209133-Nevus, Pigmented,
pubmed-meshheading:11209133-Proto-Oncogene Proteins c-met,
pubmed-meshheading:11209133-Signal Transduction
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pubmed:year |
2001
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pubmed:articleTitle |
Immunohistochemical detection of the c-met proto-oncogene product in the congenital melanocytic nevus of an infant with neurocutaneous melanosis.
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pubmed:affiliation |
First Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan. hitakaya@showa.gunma-u.ac.jp
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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