Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-2-5
pubmed:abstractText
3-Modified D-myo-inositol imidazolyl ether lipid phosphates and a carbonate were synthesized and evaluated as inhibitors of P13-K and Akt. These data are presented along with IC50 values for the inhibition of the growth of three cancer cell lines.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/AKT1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Carbonic Acid, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Imidazoles, http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol Phosphates, http://linkedlifedata.com/resource/pubmed/chemical/Phospholipid Ethers, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0960-894X
pubmed:author
pubmed:issnType
Print
pubmed:day
22
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
173-6
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:11206452-Animals, pubmed-meshheading:11206452-Antineoplastic Agents, pubmed-meshheading:11206452-Carbonic Acid, pubmed-meshheading:11206452-Cell Division, pubmed-meshheading:11206452-Combinatorial Chemistry Techniques, pubmed-meshheading:11206452-Drug Screening Assays, Antitumor, pubmed-meshheading:11206452-Enzyme Inhibitors, pubmed-meshheading:11206452-Humans, pubmed-meshheading:11206452-Imidazoles, pubmed-meshheading:11206452-Inhibitory Concentration 50, pubmed-meshheading:11206452-Mice, pubmed-meshheading:11206452-Phosphatidylinositol 3-Kinases, pubmed-meshheading:11206452-Phosphatidylinositol Phosphates, pubmed-meshheading:11206452-Phospholipid Ethers, pubmed-meshheading:11206452-Protein-Serine-Threonine Kinases, pubmed-meshheading:11206452-Proto-Oncogene Proteins, pubmed-meshheading:11206452-Proto-Oncogene Proteins c-akt, pubmed-meshheading:11206452-Signal Transduction, pubmed-meshheading:11206452-Structure-Activity Relationship, pubmed-meshheading:11206452-Tumor Cells, Cultured
pubmed:year
2001
pubmed:articleTitle
3-Deoxy-3-substituted-D-myo-inositol imidazolyl ether lipid phosphates and carbonate as inhibitors of the phosphatidylinositol 3-kinase pathway and cancer cell growth.
pubmed:affiliation
Department of Neurology, Georgetown University Medical Center, Washington, DC 20007, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.