Source:http://linkedlifedata.com/resource/pubmed/id/11206347
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2001-2-6
|
| pubmed:abstractText |
We compared the prognostic factors and outcome of 30 patients with juvenile chronic arthritis (JCA) extending into adult life with those of 30 patients with adult rheumatoid arthritis (RA) at a university adult rheumatology clinic; pairs were matched for sex and duration of disease (mean 8 years). One-third of JCA patients had seronegative polyarticular disease and another third had oligoarticular disease. In a third of the JCA patients, the clinical presentation changed during the follow-up. Over half of the RA patients had seropositive polyarticular and a one-third had seronegative polyarticular disease. Fewer seropositive patients were recorded in the JCA group than in the RA group both at the beginning (16.7% versus 56.7%; p=0.003) and at the end of the follow-up (14.3% versus 59.3%; p=0.001). JCA patients developed less radiographic changes than RA patients (46.7% versus 76.7%; p=0.034); oligoarthritis in the JCA group had the best prognosis whereas seropositive polyarthritis in the RA group had the worst prognosis. Significantly more patients with JCA than RA (60% versus 23%; p=0.009) were in remission at the end of the follow-up. In conclusion, when studied in adult life, the long-term prognosis is better in patients with JCA than in those with RA.
|
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0770-3198
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
18
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
220-6
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:11206347-Adolescent,
pubmed-meshheading:11206347-Adult,
pubmed-meshheading:11206347-Aged,
pubmed-meshheading:11206347-Antirheumatic Agents,
pubmed-meshheading:11206347-Arthritis, Juvenile Rheumatoid,
pubmed-meshheading:11206347-Child,
pubmed-meshheading:11206347-Child, Preschool,
pubmed-meshheading:11206347-Disability Evaluation,
pubmed-meshheading:11206347-Female,
pubmed-meshheading:11206347-Follow-Up Studies,
pubmed-meshheading:11206347-Glucocorticoids,
pubmed-meshheading:11206347-Hospitals, University,
pubmed-meshheading:11206347-Humans,
pubmed-meshheading:11206347-Infant,
pubmed-meshheading:11206347-Joints,
pubmed-meshheading:11206347-Male,
pubmed-meshheading:11206347-Middle Aged,
pubmed-meshheading:11206347-Prognosis,
pubmed-meshheading:11206347-Remission Induction,
pubmed-meshheading:11206347-Serologic Tests
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Juvenile chronic arthritis in adult life: a study of long-term outcome in patients with juvenile chronic arthritis or adult rheumatoid arthritis.
|
| pubmed:affiliation |
Department of Medicine, Helsinki University Central Hospital, Finland.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|