| pubmed-article:11205358 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11205358 | lifeskim:mentions | umls-concept:C0026769 | lld:lifeskim |
| pubmed-article:11205358 | lifeskim:mentions | umls-concept:C0033325 | lld:lifeskim |
| pubmed-article:11205358 | lifeskim:mentions | umls-concept:C0033522 | lld:lifeskim |
| pubmed-article:11205358 | pubmed:issue | 4 Suppl 2 | lld:pubmed |
| pubmed-article:11205358 | pubmed:dateCreated | 2001-2-2 | lld:pubmed |
| pubmed-article:11205358 | pubmed:abstractText | Two hundred and twenty-four patients at their first diagnosis of multiple sclerosis (MS) were prospectively followed for a mean period of 9.78 years. We considered as endpoints the time to reach non-reversible disability levels corresponding to EDSS scores of 4.0 and 6.0, and the beginning of a secondary progressive phase in the relapsing-remitting subgroup of patients. An initially progressive course and higher basal EDSS scores proved to be the best predictors of unfavorable prognosis. A greater number of functional systems involved at onset as well as higher residual deficits in pyramidal, visual, sphincteric and cerebellar systems were other factors predictive of a poor outcome, whereas sensory system involvement turned out to be favorable. A longer first inter-attack interval was associated with a better prognosis. However, overall number of relapses in the first two years of the disease was of no prognostic value. The presence of oligoclonal banding in the cerebrospinal fluid and a cerebral MRI exam strongly suggestive or suggestive of MS in the early phases of the disease were associated with a higher probability of a worse outcome. | lld:pubmed |
| pubmed-article:11205358 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11205358 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11205358 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11205358 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11205358 | pubmed:issn | 1590-1874 | lld:pubmed |
| pubmed-article:11205358 | pubmed:author | pubmed-author:AmatoM PMP | lld:pubmed |
| pubmed-article:11205358 | pubmed:author | pubmed-author:PonzianiGG | lld:pubmed |
| pubmed-article:11205358 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11205358 | pubmed:volume | 21 | lld:pubmed |
| pubmed-article:11205358 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11205358 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11205358 | pubmed:pagination | S831-8 | lld:pubmed |
| pubmed-article:11205358 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:meshHeading | pubmed-meshheading:11205358... | lld:pubmed |
| pubmed-article:11205358 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:11205358 | pubmed:articleTitle | A prospective study on the prognosis of multiple sclerosis. | lld:pubmed |
| pubmed-article:11205358 | pubmed:affiliation | Department of Neurology, University of Florence, Italy. | lld:pubmed |
| pubmed-article:11205358 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11205358 | lld:pubmed |
