Linked Life Data

11205197

Source:http://linkedlifedata.com/resource/pubmed/id/11205197

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6C
pubmed:dateCreated
2001-2-6
pubmed:abstractText
Tissue polypeptide specific antigen (TPS) is a new tumor marker that indicates tumor proliferative rate rather than tumor burden. The purpose of this study is to assess the clinical value of TPS in patients with nasopharyngeal carcinoma (NPC). Serum levels of TPS were measured in 60 patients with untreated NPC including 36 squamous cell carcinomas (SCC) and 24 undifferentiated carcinomas. NPC patients were separated into different subgroups based on the International Union Against Cancer (UICC) TNM classification system. Forty three healthy subjects without any evidence of malignancy or other systemic diseases were included as controls. The results showed that (1) the mean serum TPS level of the NPC patients was significantly higher than that of the healthy controls, (2) the mean serum TPS level of NPC patients with SCC was significantly higher than patients with undifferentiated carcinomas, (3) the mean serum TPS levels of NPC patients with higher TNM stages were significantly higher than those with lower TNM stages, (4) the overall diagnostic sensitivity of TPS for NPC is 58.3%, and (5) the overall diagnostic sensitivities of TPS in NPC patients with undifferentiated carcinomas and higher TNM stages were significantly higher than those with SCC and lower TNM stages. In conclusion, our results suggest that TPS may have a potential clinical role as a valuable tumor marker for NPC.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0250-7005
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4661-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Tissue polypeptide specific antigen (TPS) as a tumor marker in nasopharyngeal carcinoma.
pubmed:affiliation
Department of Nuclear Medicine, China Medical College Hospital, Taichug, Taiwan.
pubmed:publicationType
Journal Article