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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2001-2-2
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pubmed:databankReference |
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pubmed:abstractText |
The complete nucleotide sequence of columbid circovirus (CoCV) isolated from pigeons is described. CoCV was amplified using a consensus primer PCR approach directed against conserved sequences within the rep genes of vertebrate circoviruses. The genome of CoCV is circular and 2037 nt in size. It displays 55% homology to the genome of psittacine beak and feather disease virus and is more distantly related (< 40% homology) to porcine circovirus type 1 and 2. Two major open reading frames were identified, encoding the replicase and the putative capsid protein of CoCV. A region similar to the origin of replication of other circoviruses was found: it encompasses a stem-loop structure with the nonamer 5'-TAGTATTAC, conserved in circo-, nano- and geminiviruses. Phylogenetic analyses suggest classification of CoCV as member of the genus Circovirus of the virus family Circoviridae.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0304-8608
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2469-79
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11205099-Amino Acid Sequence,
pubmed-meshheading:11205099-Animals,
pubmed-meshheading:11205099-Capsid,
pubmed-meshheading:11205099-Circovirus,
pubmed-meshheading:11205099-Cloning, Molecular,
pubmed-meshheading:11205099-Columbidae,
pubmed-meshheading:11205099-DNA Helicases,
pubmed-meshheading:11205099-DNA Primers,
pubmed-meshheading:11205099-DNA-Binding Proteins,
pubmed-meshheading:11205099-Genome, Viral,
pubmed-meshheading:11205099-Molecular Sequence Data,
pubmed-meshheading:11205099-Open Reading Frames,
pubmed-meshheading:11205099-Phylogeny,
pubmed-meshheading:11205099-Sequence Alignment,
pubmed-meshheading:11205099-Trans-Activators
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pubmed:year |
2000
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pubmed:articleTitle |
Cloning and sequencing of columbid circovirus (coCV), a new circovirus from pigeons.
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pubmed:affiliation |
P24 (Xenotransplantation), Robert Koch-Institut, Berlin, Germany.
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pubmed:publicationType |
Journal Article
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