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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1975-6-20
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pubmed:abstractText |
Skin tests to various common antigens, dinitrochlorobenzene, and 5-fluorouracil (5-FU) were performed on patients being treated for cutaneous neoplasms with topical 5-FU cream. Eleven of 15 patients tested both before and after therapy converted from skin test negative to positive with respect to 5-FU. This conversion correlated with positive dinitrochlorobenzene skin tests and therapeutic cure. The relation between the induction of delayed hypersensitivity reactions to 5-FU following treatment with topical 5-FU and the cure rate for cutaneous neoplasms showed a trend toward correlation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0008-5472
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1288-94
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1120313-Administration, Topical,
pubmed-meshheading:1120313-Biopsy,
pubmed-meshheading:1120313-Carcinoma, Basal Cell,
pubmed-meshheading:1120313-Carcinoma, Basosquamous,
pubmed-meshheading:1120313-Carcinoma, Squamous Cell,
pubmed-meshheading:1120313-Carcinoma in Situ,
pubmed-meshheading:1120313-Fluorouracil,
pubmed-meshheading:1120313-Humans,
pubmed-meshheading:1120313-Hypersensitivity, Delayed,
pubmed-meshheading:1120313-Immunoglobulin G,
pubmed-meshheading:1120313-Immunoglobulin M,
pubmed-meshheading:1120313-Nitrobenzenes,
pubmed-meshheading:1120313-Skin Neoplasms,
pubmed-meshheading:1120313-Skin Tests
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pubmed:year |
1975
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pubmed:articleTitle |
Delayed hypersensitivity to 5-fluorouracil following topical chemotherapy of cutaneous cancers.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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