Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2001-1-29
pubmed:abstractText
A few uncommon but distinctive tumors may preferentially involve the paratestis. The 3 unusual tumors that represent the focus of this discussion are the ovarian-type epithelial tumors (OTET), the desmoplastic small round cell tumor (DSRCT), and the melanotic neuroectodermal tumor of infancy (MNTI). The OTETs are testicular homologues of their more common namesake counterparts that arise in the ovary. Most frequent of these are serous tumors of borderline malignancy, with fewer cases of serous carcinomas or other forms of mullerian differentiation. DSRCT is an increasingly recognized, aggressive, "small blue cell" neoplasm with distinctive clinical and pathologic features. These polyphenotypic tumors characteristically, but not invariably, arise in intimate association with the serosal membrane of the peritoneal cavity and harbor a signature translocation-t(11;22)(p13,q12). In the paratestis they often involve the surface of the epididymis. The MNTI is an enigmatic, histologically distinctive, low-grade neoplasm occasionally encountered in the epididymis. Recognition of its features is essential to avoid misdiagnosis as a more aggressive "small blue cell" neoplasm and consequent therapeutic mismanagement. Primary hematopoietic tumors of the paratesticular structures are rare. There appears to be a tendency for young men to have low-grade lymphomas with an indolent course and older patients to develop higher-grade tumors. Plasmacytoma and granulocytic sarcoma of the paratestis are even more rare and are often susceptible to misinterpretation. Finally, metastatic tumors and a variety of other very rare neoplasms are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0740-2570
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
319-39
pubmed:dateRevised
2007-5-16
pubmed:meshHeading
pubmed-meshheading:11202548-Adolescent, pubmed-meshheading:11202548-Carcinoma, Small Cell, pubmed-meshheading:11202548-Child, pubmed-meshheading:11202548-Child, Preschool, pubmed-meshheading:11202548-Female, pubmed-meshheading:11202548-Humans, pubmed-meshheading:11202548-Infant, pubmed-meshheading:11202548-Infant, Newborn, pubmed-meshheading:11202548-Leukemia, Myeloid, pubmed-meshheading:11202548-Lymphoma, pubmed-meshheading:11202548-Male, pubmed-meshheading:11202548-Middle Aged, pubmed-meshheading:11202548-Neoplasm Metastasis, pubmed-meshheading:11202548-Neoplasms, Connective Tissue, pubmed-meshheading:11202548-Neoplasms, Glandular and Epithelial, pubmed-meshheading:11202548-Neuroectodermal Tumor, Melanotic, pubmed-meshheading:11202548-Plasmacytoma, pubmed-meshheading:11202548-Testicular Neoplasms
pubmed:year
2000
pubmed:articleTitle
Miscellaneous rare paratesticular tumors.
pubmed:affiliation
Department of Pathology, Indiana University School of Medicine, Indianapolis, USA.
pubmed:publicationType
Journal Article, Review