| pubmed-article:11196152 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11196152 | lifeskim:mentions | umls-concept:C0042776 | lld:lifeskim |
| pubmed-article:11196152 | lifeskim:mentions | umls-concept:C0025663 | lld:lifeskim |
| pubmed-article:11196152 | lifeskim:mentions | umls-concept:C0056997 | lld:lifeskim |
| pubmed-article:11196152 | lifeskim:mentions | umls-concept:C0205341 | lld:lifeskim |
| pubmed-article:11196152 | lifeskim:mentions | umls-concept:C0439851 | lld:lifeskim |
| pubmed-article:11196152 | lifeskim:mentions | umls-concept:C1515035 | lld:lifeskim |
| pubmed-article:11196152 | lifeskim:mentions | umls-concept:C1517499 | lld:lifeskim |
| pubmed-article:11196152 | lifeskim:mentions | umls-concept:C1552596 | lld:lifeskim |
| pubmed-article:11196152 | lifeskim:mentions | umls-concept:C1947931 | lld:lifeskim |
| pubmed-article:11196152 | lifeskim:mentions | umls-concept:C1517564 | lld:lifeskim |
| pubmed-article:11196152 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:11196152 | pubmed:dateCreated | 2001-1-19 | lld:pubmed |
| pubmed-article:11196152 | pubmed:abstractText | To investigate the feasibility of repeated gene transfection in suicide gene therapy against human solid tumors by a combination of 5- fluorocytosine (5-FC) and its converting enzyme, cytosine deaminase (CD), we repeatedly transfected the yeast CD gene into the human pancreatic cancer cell line BXPC3 using the hemagglutinating virus of Japan-liposome in a new gene transfer method. The in vivo growth of the s.c. transplanted BXPC3 tumor in nude mice given CD-gene transfection was significantly suppressed by i.p. injection of 5-FC when compared with tumors treated with the control vector. Furthermore, the tumor transfected with the CD gene during a 7-day interval was suppressed much more than that of a single transfection. These results suggest that repeated transfection of the suicide gene together with the combination of 5-FC and the yeast CD gene using the hemagglutinating virus of Japan-liposome gene transfer method may be useful for the treatment of human solid tumors, including pancreatic cancer. | lld:pubmed |
| pubmed-article:11196152 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11196152 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11196152 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11196152 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11196152 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11196152 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11196152 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11196152 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11196152 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11196152 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11196152 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11196152 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:11196152 | pubmed:issn | 0008-5472 | lld:pubmed |
| pubmed-article:11196152 | pubmed:author | pubmed-author:YamanoTT | lld:pubmed |
| pubmed-article:11196152 | pubmed:author | pubmed-author:MiyoshiYY | lld:pubmed |
| pubmed-article:11196152 | pubmed:author | pubmed-author:SekimotoMM | lld:pubmed |
| pubmed-article:11196152 | pubmed:author | pubmed-author:KanedaYY | lld:pubmed |
| pubmed-article:11196152 | pubmed:author | pubmed-author:MondenMM | lld:pubmed |
| pubmed-article:11196152 | pubmed:author | pubmed-author:AiharaTT | lld:pubmed |
| pubmed-article:11196152 | pubmed:author | pubmed-author:TamakiYY | lld:pubmed |
| pubmed-article:11196152 | pubmed:author | pubmed-author:TomitaNN | lld:pubmed |
| pubmed-article:11196152 | pubmed:author | pubmed-author:SenterP DPD | lld:pubmed |
| pubmed-article:11196152 | pubmed:author | pubmed-author:SakitaII | lld:pubmed |
| pubmed-article:11196152 | pubmed:author | pubmed-author:OhueMM | lld:pubmed |
| pubmed-article:11196152 | pubmed:author | pubmed-author:KanyamaHH | lld:pubmed |
| pubmed-article:11196152 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11196152 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:11196152 | pubmed:volume | 61 | lld:pubmed |
| pubmed-article:11196152 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11196152 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11196152 | pubmed:pagination | 14-8 | lld:pubmed |
| pubmed-article:11196152 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:meshHeading | pubmed-meshheading:11196152... | lld:pubmed |
| pubmed-article:11196152 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11196152 | pubmed:articleTitle | Usefulness of repeated direct intratumoral gene transfer using hemagglutinating virus of Japan-liposome method for cytosine deaminase suicide gene therapy. | lld:pubmed |
| pubmed-article:11196152 | pubmed:affiliation | Department of Surgery II, Osaka University Medical School, Suita, Japan. h-kan@qf6.s0-net.nc.jp | lld:pubmed |
| pubmed-article:11196152 | pubmed:publicationType | Journal Article | lld:pubmed |
