Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1975-5-29
pubmed:abstractText
Morphological investigations by lightmicroscopy were performed to evaluate the influence of an altered liver RES-function state on the course of Gal-N-hepatitis. There was a good correlation between the biochemical data and the morphological alterations. The simultaneous infusion of Gal-N 1 g/kg b.w. and carbon particles (2.6 mg/100 g b.w) into the portal vein was followed by subtotal necrosis of the liver and Sanarelli-Shwartzmann-phenomenon. Signs of RES-activity were nearly absent. 8 days after pretreatment with carbon, Gal-N application did not produce Gal-N hepatitis; 21 days after carbon infusion the morphological changes normally found after Gal-N application were present. The morphological studies confirm the concept that an altered RES-function state is a very important factor for the development of liver cell necrosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0300-970X
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-35
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Galactosamine- "hepatitis" in rats with different phagocytic activity of liver RES.
pubmed:publicationType
Journal Article