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rdf:type |
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lifeskim:mentions |
umls-concept:C0003250,
umls-concept:C0004096,
umls-concept:C0014467,
umls-concept:C0021759,
umls-concept:C0205087,
umls-concept:C0332206,
umls-concept:C0458827,
umls-concept:C0871261,
umls-concept:C1280500,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
9248
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pubmed:dateCreated |
2001-1-12
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pubmed:abstractText |
Interleukin-5 (IL-5) is essential for the formation of eosinophils, which are thought to have a major role in the pathogenesis of asthma and other allergic diseases. We aimed to assess the effects of monoclonal antibody to IL-5 on blood and sputum eosinophils, airway hyper-responsiveness, and the late asthmatic reaction to inhaled allergen in patients with mild asthma.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0140-6736
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pubmed:author |
pubmed-author:BarneyP LPL,
pubmed-author:ChungK FKF,
pubmed-author:CowleyH CHC,
pubmed-author:DiamantZZ,
pubmed-author:DjukanovicRR,
pubmed-author:HaltonMM,
pubmed-author:HolgateS TST,
pubmed-author:KhanJJ,
pubmed-author:LeckieM JMJ,
pubmed-author:MathurA KAK,
pubmed-author:O'ConnorB JBJ,
pubmed-author:SterkP JPJ,
pubmed-author:WallsC MCM,
pubmed-author:ten BrinkeAA
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pubmed:issnType |
Print
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pubmed:volume |
356
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2144-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11191542-Adult,
pubmed-meshheading:11191542-Analysis of Variance,
pubmed-meshheading:11191542-Antibodies, Monoclonal,
pubmed-meshheading:11191542-Asthma,
pubmed-meshheading:11191542-Bronchial Provocation Tests,
pubmed-meshheading:11191542-Double-Blind Method,
pubmed-meshheading:11191542-Eosinophils,
pubmed-meshheading:11191542-Histamine,
pubmed-meshheading:11191542-Humans,
pubmed-meshheading:11191542-Infusions, Intravenous,
pubmed-meshheading:11191542-Interleukin-5,
pubmed-meshheading:11191542-Leukocyte Count,
pubmed-meshheading:11191542-Male,
pubmed-meshheading:11191542-Sputum
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pubmed:articleTitle |
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.
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pubmed:affiliation |
National Heart and Lung Institute, Imperial College, London, UK.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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