Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1975-5-29
pubmed:abstractText
Previous studies have shown that arginine-stimulated gastrin release disappears after pyloric antrectomy in the human, while conflicting evidence indicates that gastrin is released by the human duodenum. The present study reconciles this conflict by showing that the major form of gastrin in the pyloric antrum is the heptadecpeptide form, while the duodenum contains mainly "big" and almost no heptadecapeptide gastrin. Fasting serum samples contain mostly "big" gastrins, while stimulated serum contains increased proportions of the heptadecapeptide and minigastrin species. It is suggested that local factors operative at the different G-cell sites determine the nature of gastrin released since "big" gastrins occur in most sites containing gastrin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0256-9574
pubmed:author
pubmed:issnType
Print
pubmed:day
22
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
255-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Gastrins in human antrum, duodenum and peripheral circulation.
pubmed:publicationType
Journal Article