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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1400
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|
pubmed:dateCreated |
2001-1-17
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|
pubmed:abstractText |
Recent advances in measuring T-cell responses to viruses have led to new insights into how these T cells respond. In the acute infection there are massive CD8+ T-cell responses to both Epstein-Barr virus (EBV) and to human immunodeficiency virus (HIV). Many of these T cells are effector cells and only a minority appear to be capable of maintaining immunological memory. In persistent virus infections, high levels of antigen-specific effector cells persist. If virus does not persist, the effectors fade in number but memory is maintained and is primed to react rapidly to a new challenge. A vaccine that stimulates only T-cell responses may protect when these memory cells respond rapidly enough to generate high numbers of effectors before the infecting virus becomes established.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-10075982,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-10201942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-10203028,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-10227983,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-10229228,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-10229229,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-10438842,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-10545993,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-10661408,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-10716497,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-10794056,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-1721107,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-8207839,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-8810254,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9018241,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9094625,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9294140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9367954,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9491998,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9491999,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9516110,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9546783,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9565629,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9565632,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9620679,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9696847,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9811759,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9858507,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9933172,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11186301-9973448
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
|
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pubmed:issn |
0962-8436
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
29
|
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pubmed:volume |
355
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1007-11
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
|
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pubmed:year |
2000
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pubmed:articleTitle |
The dynamics of the cellular immune response to HIV infection: implications for vaccination.
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pubmed:affiliation |
MRC Human Immunology Unit, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK.
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pubmed:publicationType |
Journal Article,
Review
|
