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pubmed-article:11182618pubmed:abstractTextThe therapeutic efficacy of interleukin-2 (IL-2) has been limited by a dose-dependent vascular leak syndrome. This may be related to neutrophil-mediated endothelial injury. Taurine has been shown to decrease this injury in vitro. This study investigates the role of taurine in preventing IL-2-induced lung injury, and the role of neutrophil-endothelial interactions in mediating this injury.lld:pubmed
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pubmed-article:11182618pubmed:articleTitleTaurine prevents interleukin-2-induced acute lung injury in rats.lld:pubmed
pubmed-article:11182618pubmed:affiliationDepartment of Surgery, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland.lld:pubmed
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pubmed-article:11182618pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed