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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2001-2-22
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pubmed:abstractText |
The therapeutic efficacy of interleukin-2 (IL-2) has been limited by a dose-dependent vascular leak syndrome. This may be related to neutrophil-mediated endothelial injury. Taurine has been shown to decrease this injury in vitro. This study investigates the role of taurine in preventing IL-2-induced lung injury, and the role of neutrophil-endothelial interactions in mediating this injury.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0014-312X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
347-52
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11182618-Acute Disease,
pubmed-meshheading:11182618-Animals,
pubmed-meshheading:11182618-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:11182618-Capillary Permeability,
pubmed-meshheading:11182618-Cell Adhesion,
pubmed-meshheading:11182618-Cell Movement,
pubmed-meshheading:11182618-Interleukin-2,
pubmed-meshheading:11182618-Leukocytes,
pubmed-meshheading:11182618-Lung,
pubmed-meshheading:11182618-Lung Injury,
pubmed-meshheading:11182618-Male,
pubmed-meshheading:11182618-Neutrophils,
pubmed-meshheading:11182618-Peroxidase,
pubmed-meshheading:11182618-Proteins,
pubmed-meshheading:11182618-Rats,
pubmed-meshheading:11182618-Rats, Sprague-Dawley,
pubmed-meshheading:11182618-Splanchnic Circulation,
pubmed-meshheading:11182618-Taurine
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pubmed:year |
2000
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pubmed:articleTitle |
Taurine prevents interleukin-2-induced acute lung injury in rats.
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pubmed:affiliation |
Department of Surgery, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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