Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1975-5-29
pubmed:abstractText
Over the last twenty years drug therapy for the newborn and young infant has developed from its empirical origins to a state where the results of intensive research can be applied. As biochemical studies have shown, enzyme activities and the mechanisms of detoxification are dependent on age. These findings have prompted pharmacokinetic considerations with regard to dosage, especially in repetitive dosage regimens. Further aspects include interference and in particular the protein-binding of drugs in the newborn, side effects of drugs administered to the expectant mother, only seen later in their infants, and side effects characteristic for the newborn. Finally mention is made of some recent advances in pediatric antimicrobial therapy. The most frequent side effect is the inefficiency of drugs because of underdosage.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0026-9298
pubmed:author
pubmed:issnType
Print
pubmed:volume
123
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
15-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
[Drug therapy in newborns and young babies].
pubmed:publicationType
Journal Article, English Abstract