Source:http://linkedlifedata.com/resource/pubmed/id/11172968
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2001-2-22
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pubmed:abstractText |
Interstitial brachytherapy treatment plans are conventionally optimized with respect to total target dose and dose homogeneity, which does not account for the biologic effects of dose rate. In an HDR implant, with a stepping source, the dose rate dramatically changes during the course of treatment, depending on location, as the source moves from dwell position to dwell position. These widely varying dose rates, together with the related sequencing of the dwell positions, may impart different biologic effects at points receiving the same total dose. This study applies radiobiologic principles to account for the potential biologic impact of dose delivery at varying dose rates within an HDR implant.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0360-3016
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
839-45
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pubmed:meshHeading |
pubmed-meshheading:11172968-Algorithms,
pubmed-meshheading:11172968-Brachytherapy,
pubmed-meshheading:11172968-Cell Survival,
pubmed-meshheading:11172968-Linear Models,
pubmed-meshheading:11172968-Radiobiology,
pubmed-meshheading:11172968-Radiotherapy Dosage,
pubmed-meshheading:11172968-Relative Biological Effectiveness
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pubmed:year |
2001
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pubmed:articleTitle |
Biologic treatment planning for high-dose-rate brachytherapy.
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pubmed:affiliation |
Department of Radiation Oncology, Medical College of Virginia Hospitals of Virginia Commonwealth University (VCU), P.O. Box 980058, Richmond, VA 23298-0058, USA.
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pubmed:publicationType |
Journal Article
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