Linked Life Data

11172870

Source:http://linkedlifedata.com/resource/pubmed/id/11172870

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2001-2-22
pubmed:abstractText
Kraepelin had a modern vision of affective illness. He hypothesized that affective recurrences arose from enduring dispositions of depressive, cyclothymic, irritable, or 'manic' types. These dispositions appeared as 'temperaments' in English translations of his work. In the extreme, such temperamental gloominess or moodiness is today officially diagnosed as 'dysthymic' or 'cyclothymic'; irritable and hyperthymic (or manic) dispositions have not received official sanction in the contemporary psychiatric nomenclature. This paper reviews recent research which supports Kraepelin's theoretical framework regarding dysthymic and cyclothymic dispositions both as clinically relevant extreme forms of temperament and as precursors of major affective episodes. Compelling lines of evidence along epidemiologic, clinical-descriptive, familial-genetic, therapeutic, and follow-up perspectives are summarized for each disposition. Much of what in contemporary psychiatry is considered to be in the realm of subthreshold affective conditions, overlaps considerably with Kraepelin's concepts of the trait affective dispositions described herein. Most importantly, although Kraepelin's observations were based primarily on hospitalized, severely ill affective patients, his broad vision still guides us today for understanding etiology and instituting public health and preventive measures in major affective episodes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0165-0327
pubmed:author
pubmed:issnType
Print
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
17-31
pubmed:dateRevised
2009-9-28
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Dysthymia and cyclothymia in psychiatric practice a century after Kraepelin.
pubmed:affiliation
VA Psychiatry Service (116A), 3350 La Jolla Village Drive, San Diego, CA 92161, USA. hakiskal@ucsd.edu
pubmed:publicationType
Journal Article, Review