Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2001-2-19
pubmed:abstractText
The aim of the present study was to evaluate bone formation following maxillary sinus augmentation using bovine bone substitute material Bio-Oss in combination with venous blood by means of histologic and histomorphometric examination of human biopsies. This involved a total of 15 sinus floor elevation procedures being carried out on 11 patients (average age of 49.6 years) according to the technique described by Tatum (1986). The subantral sinus cavity was augmented using bovine apatite combined with venous blood. After an average healing phase of 6.8 months, trephine burrs were used to take 22 bone biopsies from the augmented sinus region. Then 38 Brånemark implants were inserted in both the osteotomies resulting from bone sampling and in regular sites in the augmented posterior maxilla. Histomorphometric analysis of ground sections from the bone biopsies prepared according to the standard method of Donath & Breuner (1982) produced an average percentage of newly-formed bone of 14.7% (+/- 5.0%) and a proportion of residual xenogenic bone substitute material of 29.7% (+/- 7.8%). Some 29.1% (+/- 8.1%) of the surface of the Bio-Oss granulate was in direct contact with newly-formed bone. Histologically, newly-developed bone became evident, partly invaginating the particles of apatite and forming bridges in the form of trabeculae between the individual Bio-Oss particles. Despite the absence of osteoclastic activity, the inward growth of bone indicates slow resorption of the xenogenic bone graft material. When the implants were uncovered, after an average healing phase of 6 months, 4 of the 38 implants had become loose. Of these 4 implants, 1 had to be subsequently explanted, while the others remained as "sleeping implants" and were not included in the implants superstructure. Thus, the resulting clinical survival rate, prior to prosthetic loading, was 89.5%.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0905-7161
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
217-29
pubmed:dateRevised
2006-4-17
pubmed:meshHeading
pubmed-meshheading:11168213-Adult, pubmed-meshheading:11168213-Animals, pubmed-meshheading:11168213-Biopsy, pubmed-meshheading:11168213-Blood, pubmed-meshheading:11168213-Bone Matrix, pubmed-meshheading:11168213-Bone Regeneration, pubmed-meshheading:11168213-Bone Substitutes, pubmed-meshheading:11168213-Bone Transplantation, pubmed-meshheading:11168213-Cattle, pubmed-meshheading:11168213-Collagen, pubmed-meshheading:11168213-Dental Implantation, Endosseous, pubmed-meshheading:11168213-Female, pubmed-meshheading:11168213-Guided Tissue Regeneration, Periodontal, pubmed-meshheading:11168213-Humans, pubmed-meshheading:11168213-Male, pubmed-meshheading:11168213-Maxillary Sinus, pubmed-meshheading:11168213-Membranes, Artificial, pubmed-meshheading:11168213-Middle Aged, pubmed-meshheading:11168213-Minerals, pubmed-meshheading:11168213-Oral Surgical Procedures, Preprosthetic, pubmed-meshheading:11168213-Transplantation, Heterologous
pubmed:year
2000
pubmed:articleTitle
Maxillary sinus augmentation using xenogenic bone substitute material Bio-Oss in combination with venous blood. A histologic and histomorphometric study in humans.
pubmed:affiliation
Department of Prosthodontics, University of Aachen, Germany.
pubmed:publicationType
Journal Article, Clinical Trial