Source:http://linkedlifedata.com/resource/pubmed/id/11167833
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2001-2-22
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pubmed:abstractText |
We report the case of a young Caucasian man who presented with polyneuropathy and severe, ultimately fatal, congestive heart failure in the context of a chronic active Epstein-Barr virus (EBV) infection. Post-mortem examination revealed both monoclonal and polyclonal proliferation of EBV-positive atypical T lymphocytes within different organs. Predominant infiltration of the nervous system and heart with extensive myocardial scarring accounted for the clinical symptoms. The remarkable features of this case are (i) the occurrence in a Caucasian patient, (ii) the absence of detectable immunodeficiency, and (iii) the myocardial destruction by EBV-infected monoclonal T cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0007-1048
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
112
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
377-80
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11167833-Adult,
pubmed-meshheading:11167833-Epstein-Barr Virus Infections,
pubmed-meshheading:11167833-European Continental Ancestry Group,
pubmed-meshheading:11167833-Fatal Outcome,
pubmed-meshheading:11167833-Heart,
pubmed-meshheading:11167833-Heart Failure,
pubmed-meshheading:11167833-Humans,
pubmed-meshheading:11167833-Lymphoproliferative Disorders,
pubmed-meshheading:11167833-Male,
pubmed-meshheading:11167833-T-Lymphocytes
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pubmed:year |
2001
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pubmed:articleTitle |
Fatal atypical T-cell proliferation associated with Epstein-Barr virus infection.
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pubmed:affiliation |
Institute of Pathology and Department of Rheumatology, Charité Hospital Berlin, and Institute of Pathology, University Erlangen, Erlangen, Germany. steffen.hauptmann@charite.de
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pubmed:publicationType |
Journal Article,
Case Reports
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