Source:http://linkedlifedata.com/resource/pubmed/id/11165440
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2001-2-22
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pubmed:abstractText |
The somatosensory system is capable of functional reorganization following peripheral denervation or training. Studies on human amputees with phantom limb pain provided evidence that these reorganizational changes are modulated through nociceptive input. In the present study we used magnetoencephalographic recordings of six healthy volunteers to assess whether acute pain by itself causes a reorganization of the primary somatosensory cortex. After the induction of an intense experimental pain at the thenar of the left hand by intradermal injection of capsaicin, the extent of the cortical hand representation and the distance between the hand representation and the localization of the lip decreased. A likely mechanism for this acute reorganization is that pain induced hyperresponsiveness of the left thenar to tactile input from neighboring body sites.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
9
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pubmed:volume |
298
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11165440-Acute Disease,
pubmed-meshheading:11165440-Adult,
pubmed-meshheading:11165440-Capsaicin,
pubmed-meshheading:11165440-Evoked Potentials, Somatosensory,
pubmed-meshheading:11165440-Hand,
pubmed-meshheading:11165440-Humans,
pubmed-meshheading:11165440-Magnetoencephalography,
pubmed-meshheading:11165440-Male,
pubmed-meshheading:11165440-Nerve Fibers,
pubmed-meshheading:11165440-Neuronal Plasticity,
pubmed-meshheading:11165440-Nociceptors,
pubmed-meshheading:11165440-Pain,
pubmed-meshheading:11165440-Somatosensory Cortex
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pubmed:year |
2001
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pubmed:articleTitle |
Functional reorganization of the human primary somatosensory cortex after acute pain demonstrated by magnetoencephalography.
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pubmed:affiliation |
Department of Neurology, University of Münster, Albert Schweitzer-Strasse 33, 48129, Münster, Germany. soros@uni-muenster.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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