Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2001-2-22
pubmed:databankReference
pubmed:abstractText
In a previous study, we found avian sarcoma and leukosis virus (ASLV) gag genes in 19 species of birds in the order Galliformes including all grouse and ptarmigan (Tetraoninae) surveyed. Our data suggested that retroviruses had been transmitted horizontally among some host species. To further investigate these elements, we sequenced a replication-defective retrovirus, here named tetraonine endogenous retrovirus (TERV), from Bonasa umbellus (ruffed grouse). This is the first report of a complete, replication-defective ASLV provirus sequence from any bird other than the domestic chicken. We found a replication-defective proviral sequence consisting of putative Gag and Env proteins flanked by long terminal repeats. Reverse transcription-PCR analysis showed that retroviral gag sequences closely related to TERV are transcribed, supporting the hypothesis that TERV is an active endogenous retrovirus. Phylogenetic analyses suggest that TERV may have arisen via recombination between different retroviral lineages infecting birds. Southern blotting using gag probes showed that TERV occurs in tetraonines but not in chickens or ducks, suggesting that integration occurred after the earliest phasianid divergences but prior to the radiation of tetraonine birds.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-10329189, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-10364281, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-10590135, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-10627540, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-10756010, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-1310773, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-1312613, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-1321278, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-1439790, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-228057, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-2398526, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-2414012, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-2815581, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-3524858, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-6286997, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-6291784, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-6299578, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-7904558, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-7904657, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-8083996, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-9207241, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-9254694, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-9396791, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-9621088, http://linkedlifedata.com/resource/pubmed/commentcorrection/11160701-9847216
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-538X
pubmed:author
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2002-9
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:11160701-Amino Acid Sequence, pubmed-meshheading:11160701-Animals, pubmed-meshheading:11160701-Avian Sarcoma Viruses, pubmed-meshheading:11160701-Avian leukosis virus, pubmed-meshheading:11160701-Bacteriophage lambda, pubmed-meshheading:11160701-Base Sequence, pubmed-meshheading:11160701-Biological Evolution, pubmed-meshheading:11160701-Birds, pubmed-meshheading:11160701-Endogenous Retroviruses, pubmed-meshheading:11160701-Gene Products, gag, pubmed-meshheading:11160701-Genes, gag, pubmed-meshheading:11160701-Genomic Library, pubmed-meshheading:11160701-Molecular Sequence Data, pubmed-meshheading:11160701-Phylogeny, pubmed-meshheading:11160701-Proviruses, pubmed-meshheading:11160701-Recombination, Genetic, pubmed-meshheading:11160701-Sequence Analysis, DNA, pubmed-meshheading:11160701-Virus Replication
pubmed:year
2001
pubmed:articleTitle
Evolution and characterization of tetraonine endogenous retrovirus: a new virus related to avian sarcoma and leukosis viruses.
pubmed:affiliation
Department of Biology, University of Michigan, Ann Arbor, Michigan 48109-1079, USA. ddimcheff@nih.gov
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't