| pubmed-article:11160309 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11160309 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:11160309 | lifeskim:mentions | umls-concept:C0034790 | lld:lifeskim |
| pubmed-article:11160309 | lifeskim:mentions | umls-concept:C1511695 | lld:lifeskim |
| pubmed-article:11160309 | lifeskim:mentions | umls-concept:C0597360 | lld:lifeskim |
| pubmed-article:11160309 | lifeskim:mentions | umls-concept:C0021469 | lld:lifeskim |
| pubmed-article:11160309 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:11160309 | lifeskim:mentions | umls-concept:C1549081 | lld:lifeskim |
| pubmed-article:11160309 | lifeskim:mentions | umls-concept:C1692758 | lld:lifeskim |
| pubmed-article:11160309 | lifeskim:mentions | umls-concept:C1709305 | lld:lifeskim |
| pubmed-article:11160309 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:11160309 | pubmed:dateCreated | 2001-2-22 | lld:pubmed |
| pubmed-article:11160309 | pubmed:abstractText | A small fraction of T cells expresses killer-cell Ig-like receptors (KIR), a family of MHC class I-specific receptors that can modulate TCR-dependent activation of effector functions. Although KIR(+) cells are enriched within Ag-experienced T cell subsets, the precise relationships between KIR(+) and KIR(-) T cells and the stage of KIR induction on these lymphocytes remain unclear. In this study, we compared KIR(-) and KIR(+) alphabeta T cell clones, sorted by means of the CD158b (KIR2DL2/KIR2DL3/KIR2DS2) specific mAb GL183. We isolated several pairs of CD158b(+) and CD158b(-) alphabeta T cell clones sharing identical productive and nonproductive TCR transcripts. We showed that expression of functional KIR on T cells is regulated after termination of TCR rearrangements. Transcriptional regulation of KIR genes was documented in multiple T cell clones generated from the same donor, and the presence of KIR transcripts was also detected in KIR(-) T cells. These results document a complex regulation of KIR expression in T cells at both pre and posttranscriptional levels, under the control of yet undefined signals provided in vivo. | lld:pubmed |
| pubmed-article:11160309 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11160309 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11160309 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:11160309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11160309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11160309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11160309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11160309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11160309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11160309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11160309 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11160309 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:11160309 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:MorettaAA | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:HoussaintEE | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:VivierEE | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:BonnevilleMM | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:DavodeauFF | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:PeyratMM | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:SchleinitzNN | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:ScotetEE | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:RomagneFF | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:HalaryFF | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:VelyFF | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:SaulquinXX | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:CouedelCC | lld:pubmed |
| pubmed-article:11160309 | pubmed:author | pubmed-author:MorcetJJ | lld:pubmed |
| pubmed-article:11160309 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11160309 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:11160309 | pubmed:volume | 166 | lld:pubmed |
| pubmed-article:11160309 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11160309 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11160309 | pubmed:pagination | 2487-94 | lld:pubmed |
| pubmed-article:11160309 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:11160309 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11160309 | pubmed:articleTitle | Regulation of inhibitory and activating killer-cell Ig-like receptor expression occurs in T cells after termination of TCR rearrangements. | lld:pubmed |
| pubmed-article:11160309 | pubmed:affiliation | Institut National de la Santé et de la Recherche Médicale, Unité 463, Institut de Biologie, Nantes, France. | lld:pubmed |
| pubmed-article:11160309 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11160309 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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