Linked Life Data

11160076

Source:http://linkedlifedata.com/resource/pubmed/id/11160076

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-2-22
pubmed:abstractText
The ability of rabbit trachealis to undergo plastic adaptation to chronic shortening or lengthening was assessed by setting the muscle preparations at three lengths for 24 h in relaxed state: a reference length in which applied force was approximately 1-2% of maximal active force (P(o)) and lengths considerably shorter and longer than the reference. Passive and active length-tension (L-T) curves for the preparations were then obtained by electrical field stimulation at progressively increasing muscle length. Classically shaped L-T curves were obtained with a distinct optimal length (L(o)) at which P(o) developed; however, both the active and passive L-T curves were shifted, whereas P(o) remained unchanged. L(o) was 72% and 148% that of the reference preparations for the passively shortened and lengthened muscles, respectively. The results suggest that chronic narrowing of the airways could induce a shift in the L-T relationship of smooth muscle, resulting in a maintained potential for maximal force production.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
8750-7587
pubmed:author
pubmed:issnType
Print
pubmed:volume
90
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
734-40
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Selected contribution: effect of chronic passive length change on airway smooth muscle length-tension relationship.
pubmed:affiliation
Pulmonary Research Laboratory, St. Paul's Hospital, Vancouver, BC, Canada V6Z 1Y6.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't