rdf:type |
|
lifeskim:mentions |
umls-concept:C0001675,
umls-concept:C0002976,
umls-concept:C0027061,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0035820,
umls-concept:C0078058,
umls-concept:C0205263,
umls-concept:C0242184,
umls-concept:C0242606,
umls-concept:C0678226,
umls-concept:C1256770
|
pubmed:issue |
1-3
|
pubmed:dateCreated |
2001-1-11
|
pubmed:abstractText |
Oxidative stress, as exerted by free radicals within biological systems, is known to exert numerous physiological and pathological effects on the cardiovascular system. Short-term exposure to environmental conditions such as low oxygen tension can cause such oxidative stress in vivo through inhalational hypoxia/reoxygenation. In this report the effects of different durations of hypoxia were investigated on myocardial protein expression of vascular endothelial growth factor (VEGF). a major angiogenic growth factor, and also explore the possible modulatory role of transcription factor NFkappaB on such expression.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0300-483X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
30
|
pubmed:volume |
155
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
27-35
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:11154794-Animals,
pubmed-meshheading:11154794-Anoxia,
pubmed-meshheading:11154794-Blotting, Western,
pubmed-meshheading:11154794-DNA,
pubmed-meshheading:11154794-Endothelial Growth Factors,
pubmed-meshheading:11154794-Lymphokines,
pubmed-meshheading:11154794-Male,
pubmed-meshheading:11154794-Models, Animal,
pubmed-meshheading:11154794-Myocardial Stunning,
pubmed-meshheading:11154794-Myocardium,
pubmed-meshheading:11154794-NF-kappa B,
pubmed-meshheading:11154794-Oxidative Stress,
pubmed-meshheading:11154794-Rats,
pubmed-meshheading:11154794-Rats, Sprague-Dawley,
pubmed-meshheading:11154794-Vascular Endothelial Growth Factor A,
pubmed-meshheading:11154794-Vascular Endothelial Growth Factors
|
pubmed:year |
2000
|
pubmed:articleTitle |
Oxidative stress due to hypoxia/reoxygenation induces angiogenic factor VEGF in adult rat myocardium: possible role of NFkappaB.
|
pubmed:affiliation |
Department of Surgery, University of Connecticut School of Medicine, Farmington 06030-1110, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|