Linked Life Data

11152226

Source:http://linkedlifedata.com/resource/pubmed/id/11152226

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2001-1-9
pubmed:abstractText
The passenger leukocytes in the intestine have a lineage profile that predisposes to graft-versus-host disease (GVHD) in some animal models and have inferior tolerogenic qualities compared with the leukocytes in the liver, other solid organs, and bone marrow. Elimination by ex vivo irradiation of mature lymphoid elements from the bowel allografts is known to eliminate the GVHD risk. We hypothesized that infusion of donor bone marrow cells (BMC) in recipients of irradiated intestine would improve tolerogenesis without increasing the risk of GVHD.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0041-1337
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1632-41
pubmed:dateRevised
2010-12-3
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Immunomodulation for intestinal transplantation by allograft irradiation, adjunct donor bone marrow infusion, or both.
pubmed:affiliation
Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pennsylvania 15213, USA. murase+@pitt.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.