11147583

Source:http://linkedlifedata.com/resource/pubmed/id/11147583

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0013216, umls-concept:C0030705, umls-concept:C0162638, umls-concept:C0678222, umls-concept:C0871261, umls-concept:C1514485, umls-concept:C1704632, umls-concept:C1706817, umls-concept:C2698872, umls-concept:C2911692
pubmed:issue	11
pubmed:dateCreated	2001-1-5
pubmed:abstractText	Laboratory evidence suggests that many anticancer agents exert their effect by altering the ratio between apoptosis and cellular proliferation. The objective of this clinical study was to examine in vivo changes in apoptotic index (AI), Bcl-2 expression, proliferation (Ki-67 and S-phase fraction [SPF]), and ploidy as potential indicators of chemoresponsiveness.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0374236
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Ki-67 Antigen, http://linkedlifedata.com/resource/pubmed/chemical/Methotrexate, http://linkedlifedata.com/resource/pubmed/chemical/Mitoxantrone, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-bcl-2, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	0008-543X
pubmed:author	pubmed-author:AllredD CDC, pubmed-author:AshleyS ESE, pubmed-author:ChangJJ, pubmed-author:DowsettMM, pubmed-author:OrmerodMM, pubmed-author:PowlesT JTJ
pubmed:issnType	Print
pubmed:day	1
pubmed:volume	89
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2145-52
pubmed:dateRevised	2006-4-24
pubmed:meshHeading	pubmed-meshheading:11147583-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:11147583-Apoptosis, pubmed-meshheading:11147583-Biopsy, Needle, pubmed-meshheading:11147583-Breast Neoplasms, pubmed-meshheading:11147583-Carcinoma, pubmed-meshheading:11147583-Cell Division, pubmed-meshheading:11147583-Female, pubmed-meshheading:11147583-Flow Cytometry, pubmed-meshheading:11147583-Humans, pubmed-meshheading:11147583-Immunohistochemistry, pubmed-meshheading:11147583-Ki-67 Antigen, pubmed-meshheading:11147583-Methotrexate, pubmed-meshheading:11147583-Middle Aged, pubmed-meshheading:11147583-Mitoxantrone, pubmed-meshheading:11147583-Neoadjuvant Therapy, pubmed-meshheading:11147583-Ploidies, pubmed-meshheading:11147583-Proto-Oncogene Proteins c-bcl-2, pubmed-meshheading:11147583-S Phase, pubmed-meshheading:11147583-Tumor Markers, Biological
pubmed:year	2000
pubmed:articleTitle	Apoptosis and proliferation as predictors of chemotherapy response in patients with breast carcinoma.
pubmed:affiliation	Department of Biochemistry, Medicine and Computing, The Royal Marden Hospital, Sutton, Surrey, United Kingdom. jcchang@bcm.tmc.edu
pubmed:publicationType	Journal Article