Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2000-12-28
pubmed:abstractText
Changes in cerebral hemodynamics and oxygenation patterns in cerebral vasospasm might be underestimated if transcranial doppler sonography and angiography findings are considered singularly. This report describes preliminary findings in further development of a noninvasive method that estimates regional cerebral oxygenation and perfusion. A 50-year-old patient suffering from cerebral vasospasm after subarachnoid hemorrhage before and after superselective papaverine infusion was examined. Measurements were taken by using a technique combining indocyaningreen dye dilution and near infrared spectroscopy. Our first results suggest that the technique could be suitable for estimation of cerebral hemodynamics. This noninvasive technique can be performed at the bedside and in special environments, such as neurocritical care units. It seems to be safe, easy to perform, and less time-consuming than conventional techniques. Combination of indocyaningreen dye dilution and near infrared spectroscopy might become a powerful tool in the detection and treatment of cerebral vasospasm causing delayed cerebral ischemic deficit. Further larger-scale investigations are necessary to evaluate the diagnostic accuracy of this technique. Our preliminary observations however, based on measurements before and after superselective papaverine infusion in vasospastic vessels, helped to clarify the influence of extracerebral contamination on the cerebral near infrared spectroscopy signal in the adult head.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0898-4921
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
43-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Estimation of cerebral oxygenation and hemodynamics in cerebral vasospasm using indocyaningreen dye dilution and near infrared spectroscopy: a case report.
pubmed:affiliation
Department of Neurosurgery, University Hospital Zurich, Switzerland.
pubmed:publicationType
Journal Article, Case Reports