Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2000-12-28
pubmed:abstractText
Emerging clues about the apoptotic molecular mechanisms operating during spermatogenesis indicate that the activation mechanism of executioner caspases may diverge from the traditional signaling operating in the immune system. Two issues are now been debated: (1) Whether the massive apoptosis of spermatogenic cells observed during the first spermatogenic wave represents a mechanism for ensuring the steady state sperm output in a given segment of a seminiferous tubule. (2) Whether apoptosis just represents a local remodeling process commanded by the Sertoli cell constraints to satisfy the differentiation needs of a juxtaposed cellular domain of spermatogonial, spermatocyte, and spermatid cohorts in the adult testis.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1040-452X
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Apoptosis during spermatogenesis: the thrill of being alive.
pubmed:affiliation
Department of Cell Biology and Anatomical Sciences, The City University of New York Medical School, New York 10031, USA. kier@med.cuny.edu
pubmed:publicationType
Journal Article, Comment