Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2001-1-4
pubmed:abstractText
Transcranial magnetic stimulation (TMS) was used to measure intensity threshold, conduction of the central motor pathways (CMCT) and amplitude of the motor evoked potentials (MEPs) in 50 patients with definite form of multiple sclerosis (MS), 31 females and 19 males, aged 15 to 58 years (mean 31.9 +/- 9.8). Abnormalities in at least one parameter after TMS have been found in 76% of the cases. Interside CMCT asymmetries increased the diagnostic yield to 86% of the patients. Three MS individuals with normal clinical examination have prolonged CMCT (silent lesions). There was significant correlation between CMCT and evolution of the disease, and with the degree of pyramidal signs. CMCT correlated with cerebral motor pathway, pons, and cervical cord lesions in MRI study. TMS is an easy and reliable method to quantify pyramidal and cerebellar dysfunction in MS and monitoring the evolution of the disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0301-150X
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
441-7
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:articleTitle
Disability in multiple sclerosis. The role of transcranial magnetic stimulation.
pubmed:affiliation
Neurofisiología Clínica, Hospital La Paz, Madrid, Spain.
pubmed:publicationType
Journal Article