Source:http://linkedlifedata.com/resource/pubmed/id/11141107
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2001-1-16
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pubmed:abstractText |
Seven new marine diterpenoids having a cembrane skeleton were isolated from the Okinawan soft coral Clavularia koellikeri. Their structures were determined based on the results of spectroscopic analysis and chemical conversions. Compound 1 showed cytotoxic activity against human colorectal adenocarcinoma cells (DLD-1, IC(50) 4.2 g/mL) and strong growth inhibition against human T lymphocytic leukemia cells (MOLT-4, IC(50) 0.9 g/mL).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1647-52
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11141107-Adenocarcinoma,
pubmed-meshheading:11141107-Animals,
pubmed-meshheading:11141107-Antineoplastic Agents,
pubmed-meshheading:11141107-Cnidaria,
pubmed-meshheading:11141107-Colorectal Neoplasms,
pubmed-meshheading:11141107-Diterpenes,
pubmed-meshheading:11141107-Drug Screening Assays, Antitumor,
pubmed-meshheading:11141107-Humans,
pubmed-meshheading:11141107-Tumor Cells, Cultured
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pubmed:year |
2000
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pubmed:articleTitle |
New marine cembrane-type diterpenoids from the Okinawan soft coral Clavularia koellikeri.
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pubmed:affiliation |
Laboratory of Bioorganic Chemistry, School of Life Science, Tokyo University of Pharmacy and Life Science, Horinouchi, Hachioji, Tokyo 192-0392, Japan.
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pubmed:publicationType |
Journal Article
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