11138626

Source:http://linkedlifedata.com/resource/pubmed/id/11138626

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0242633, umls-concept:C1423842
pubmed:issue	1
pubmed:dateCreated	2001-1-2
pubmed:abstractText	After activation, CD4 helper T (Th) cells differentiate into Th1or Th2 effector subsets. These two types of cells produce distinct profiles of cytokines and regulate different immune responses. This review summarizes recent progress on different features of co-stimulatory regulation and chemokine-mediated homing of Th1 and Th2 cells. Transcription factors and signaling pathways that are selectively expressed or activated in Th1 and Th2 cells to regulate cytokine gene expression are discussed.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9430802
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	1065-6251
pubmed:author	pubmed-author:DoniAA, pubmed-author:FlavellR ARA
pubmed:issnType	Print
pubmed:volume	8
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	47-51
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:11138626-Animals, pubmed-meshheading:11138626-Gene Expression Regulation, pubmed-meshheading:11138626-Humans, pubmed-meshheading:11138626-Lymphocyte Activation, pubmed-meshheading:11138626-Signal Transduction, pubmed-meshheading:11138626-Th1 Cells, pubmed-meshheading:11138626-Th2 Cells
pubmed:year	2001
pubmed:articleTitle	Th1 and Th2 cells.
pubmed:affiliation	Department of Immunology, University of Washington School of Medicine, Seattle, USA.
pubmed:publicationType	Journal Article, Review, Research Support, Non-U.S. Gov't