Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2001-2-8
pubmed:abstractText
It is well known that gingivitis is a bacterially-elicited inflammation of the marginal gingiva. A number of chemical agents have been evaluated over the years with regard to their antimicrobial effects in the oral cavity; however, all are associated with side effects that prohibit regular long-term use. Therefore, the effectiveness of a natural Mexican Sanguinaria extract (Polygonum aviculare L.) against gingivitis, was assessed in 60 male dentistry students between the ages of 18 and 25 years. Over a period of 2 weeks, these students used the Sanguinaria extract (1 mg/ml) in oral rinse twice daily as a unique oral health measurement (no tooth-brushing was allowed). The O'Leary Plaque Index and the Löe and Silness Gingivitis Index were recorded at baseline (day 0) in all the subjects. Also, a complete prophylaxis was performed after both indices were obtained. The antibacterial and antiinflammatory effects of the extract were evaluated on days 7, 11 and 14. The results showed that the Mexican Sanguinaria extract in oral rinse significantly decreased gingivitis from day 0 (-x=1. 056) to day 14 (-x=1.011) (P</=0.05). In contrast, a significant increase in dental plaque was observed from day 0 (-x=91.38) to day 14 (-x=98.69) (P</=0.05); however, the consistency of this plaque permitted its mechanical flushing easily. From this study, it is concluded that the Mexican Sanguinaria extract in oral rinse can be employed supportively in the therapy of gingivitis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0378-8741
pubmed:author
pubmed:issnType
Print
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
45-51
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Clinical effect of a Mexican sanguinaria extract (Polygonum aviculare L.) on gingivitis.
pubmed:affiliation
Dental Research Center, School of Dentistry, Allende Ote. #151-3, Villas de San Agustin, Bo. de Santa Cruz, Metepec, C.P. 52149, Edo. de México, Mexico. mgb@coatepec.uaemex.mx
pubmed:publicationType
Journal Article, Clinical Trial