Linked Life Data

11137034

Source:http://linkedlifedata.com/resource/pubmed/id/11137034

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2001-2-5
pubmed:abstractText
In the classic model of nuclear receptor signaling, specific hormone binding results in the recruitment of coactivator proteins and transcriptional activation. Recent results with newly characterized nuclear receptors have expanded this model to include new types of ligands and novel transcriptional responses. Both inverse agonists and conventional agonist ligands have been identified for the xenobiotic receptor constitutive androstane receptor (CAR), a constitutive activator of transcription in the absence of ligands.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1043-2760
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7-10
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:articleTitle
Role reversal: new insights from new ligands for the xenobiotic receptor CAR.
pubmed:affiliation
Beth Israel Deaconness Medical Center, Dept of Medicine, Division of Endocrinology and Metabolism, 99 Brookline Avenue, Boston, MA 0221, USA.
pubmed:publicationType
Journal Article, Review