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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2001-1-9
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pubmed:abstractText |
In vitro studies support K(+)(Ca) channel-induced smooth muscle hyperpolarization as underlying acetylcholine-mediated (or bradykinin-mediated) vasodilation that persists despite combined nitric oxide (NO) and PGI(2) inhibition. We tested the hypothesis that these channels are activated by enhanced pulsatile perfusion in vivo and contribute substantially to vasodilation from this stimulus.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acetylcholine,
http://linkedlifedata.com/resource/pubmed/chemical/Apamin,
http://linkedlifedata.com/resource/pubmed/chemical/Bradykinin,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Charybdotoxin,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channel Blockers,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channels,
http://linkedlifedata.com/resource/pubmed/chemical/iberiotoxin,
http://linkedlifedata.com/resource/pubmed/chemical/omega-N-Methylarginine
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
2
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
119-24
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11136696-Acetylcholine,
pubmed-meshheading:11136696-Animals,
pubmed-meshheading:11136696-Apamin,
pubmed-meshheading:11136696-Blood Flow Velocity,
pubmed-meshheading:11136696-Bradykinin,
pubmed-meshheading:11136696-Calcium,
pubmed-meshheading:11136696-Charybdotoxin,
pubmed-meshheading:11136696-Coronary Vessels,
pubmed-meshheading:11136696-Dogs,
pubmed-meshheading:11136696-Enzyme Inhibitors,
pubmed-meshheading:11136696-Nitric Oxide,
pubmed-meshheading:11136696-Peptides,
pubmed-meshheading:11136696-Potassium,
pubmed-meshheading:11136696-Potassium Channel Blockers,
pubmed-meshheading:11136696-Potassium Channels,
pubmed-meshheading:11136696-Pulsatile Flow,
pubmed-meshheading:11136696-Signal Transduction,
pubmed-meshheading:11136696-Vasodilation,
pubmed-meshheading:11136696-omega-N-Methylarginine
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pubmed:year |
2001
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pubmed:articleTitle |
Role of calcium-sensitive K(+) channels and nitric oxide in in vivo coronary vasodilation from enhanced perfusion pulsatility.
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pubmed:affiliation |
Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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