Linked Life Data

11135281

Source:http://linkedlifedata.com/resource/pubmed/id/11135281

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2001-1-26
pubmed:abstractText
Transcranial magnetic stimulation (TMS) is a safe, noninvasive, and painless way to stimulate the human motor cortex in behaving human subjects. When it is applied as a single-pulse, measurements such as central conduction time, motor threshold, silent-period duration, recruitment curve, and mapping of muscle representation can be determined. Paired-pulse TMS is a useful way to examine cortical excitability. Single and paired-pulse TMS have been applied to study plasticity following amputation and cortical excitability in patients with dystonia. Another form of TMS is repetitive TMS (rTMS), with stimuli delivered repeatedly to a single scalp site. High-frequency rTMS can be used to transiently inactivate different cortical areas to study their functions. rTMS can also modulate cortical excitability. At stimulus frequencies higher than 5 Hz, rTMS increases cortical excitability, and stimulation around 1 Hz reduces cortical excitability. Modulation of cortical excitability by rTMS has therapeutic potential in psychiatric and neurological disorders.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:author
pubmed:copyrightInfo
Copyright 2000 John Wiley & Sons, Inc. Muscle Nerve Supplement 9:S26-S32, 2000.
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S26-32
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Studies of human motor physiology with transcranial magnetic stimulation.
pubmed:affiliation
Division of Neurology and Playfair Neuroscience Unit, Toronto Western Research Institute, University of Toronto, Toronto, Ontario, Canada. robert.chen@uhn.on.ca
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't