rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
24
|
pubmed:dateCreated |
2000-12-29
|
pubmed:abstractText |
A convenient synthesis of nonsymmetrical bivalent inhibitors of the serotonin transporter is described. The synthesis utilizes polymer-supported reagents that allow for rapid access to novel bivalent ligands without the need for isolation or purification of synthetic intermediates.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0960-894X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
18
|
pubmed:volume |
10
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2741-3
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:11133081-Animals,
pubmed-meshheading:11133081-Cross-Linking Reagents,
pubmed-meshheading:11133081-Diamines,
pubmed-meshheading:11133081-Ligands,
pubmed-meshheading:11133081-Polymers,
pubmed-meshheading:11133081-Protein Binding,
pubmed-meshheading:11133081-Rats,
pubmed-meshheading:11133081-Receptors, Adrenergic,
pubmed-meshheading:11133081-Receptors, Dopamine,
pubmed-meshheading:11133081-Serotonin Uptake Inhibitors,
pubmed-meshheading:11133081-Structure-Activity Relationship,
pubmed-meshheading:11133081-Synaptosomes
|
pubmed:year |
2000
|
pubmed:articleTitle |
A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents.
|
pubmed:affiliation |
Department of Neurology, Georgetown University Medical Center, Washington, DC 20007-2197, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|