Linked Life Data

11132371

Source:http://linkedlifedata.com/resource/pubmed/id/11132371

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2000-12-29
pubmed:abstractText
The frequency of American visceral leishmaniasis affecting humans on Margarita Island, Venezuela, has increased in recent years, and infected dogs appear to constitute the principal source of infection. ELISA tests with Leishmania donovani promastigotes and rK39 antigen from L. chagasi in serum from 541 dogs were positive in 33.1% and 21.6% of the samples, respectively. A second blood sample taken from 50 animals after 8-10 months revealed an increase from 24% to 40% of ELISA positivity to both antigens, suggesting high susceptibility and transmission in the canine population. Among 42 serologically positive dogs, 33% of which showed clinical signs of disease, 79% were positive in polymerase chain reactions using primers specific for the L. donovani complex. Control measures including epidemiological hypersurveillance, the humane sacrifice of infected dogs, and rapid diagnosis and treatment of human cases have been initiated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0035-9203
pubmed:author
pubmed:issnType
Print
pubmed:volume
94
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
484-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Canine visceral leishmaniasis on Margarita Island (Nueva Esparta, Venezuela).
pubmed:affiliation
Instituto de Biomedicina, Universidad Central de Venezuela/Ministerio de Sanidad y Asistencia Social, Apartado 4043, Caracas 1010A, Venezuela. ozerpa@telcel.net.ve
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't