GENERIC 11128639

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0596326, umls-concept:C2698197
pubmed:issue	23
pubmed:dateCreated	2000-12-20
pubmed:abstractText	Three new oligoacylated sucroses designated atractysucroses-I, -II, and -III were obtained from Atractylodis Lanceae Rhizoma as multidrug resistance (MDR) modulating substances against human carcinoma cell lines and their chemical structures were characterized as a mixture of acyl groups. Atractysucrose-I modulates MDR in KB-C2 cells as strongly as verapamil. This is the first example of an MDR-modulator classified as a carbohydrate.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	0960-894X
pubmed:author	pubmed-author:AkiyamaSS, pubmed-author:IwataEE, pubmed-author:KobayashiMM, pubmed-author:MurakamiNN, pubmed-author:TamuraSS
pubmed:issnType	Print
pubmed:day	4
pubmed:volume	10
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2629-32
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:11128639-Asteraceae, pubmed-meshheading:11128639-Drug Resistance, Multiple, pubmed-meshheading:11128639-Humans, pubmed-meshheading:11128639-Spectrum Analysis, pubmed-meshheading:11128639-Tumor Cells, Cultured
pubmed:year	2000
pubmed:articleTitle	New multidrug resistance modulators from Atractylodis Lanceae Rhizoma.
pubmed:affiliation	Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't