Source:http://linkedlifedata.com/resource/pubmed/id/11126297
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2000-12-20
|
| pubmed:abstractText |
A new tetrafluorophenol activated resin that facilitates the use of 19F NMR to quantitate loading is presented. This new resin provides a useful tool for acylation, and a novel activated polymeric sulfonate ester to generate sulfonamides. This activated resin reacts with a wide scope of N-nucleophiles including primary and secondary amines, and anilines. This new activated resin methodology provides a powerful tool for pure single-compound library synthesis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:status |
PubMed-not-MEDLINE
|
| pubmed:issn |
1520-4766
|
| pubmed:author |
pubmed-author:AireyJJ,
pubmed-author:CrawfordKK,
pubmed-author:DrewMM,
pubmed-author:EngersDD,
pubmed-author:GardyanMM,
pubmed-author:HerpinTT,
pubmed-author:KiesowTT,
pubmed-author:KrolikowskiDD,
pubmed-author:KrolikowskiPP,
pubmed-author:KumarN VNV,
pubmed-author:LabaudiniereRR,
pubmed-author:MathewRR,
pubmed-author:McGeehanGG,
pubmed-author:OrtonEE,
pubmed-author:SalvinoJ MJM
|
| pubmed:issnType |
Print
|
| pubmed:volume |
2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
691-7
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| pubmed:dateRevised |
2003-10-31
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| pubmed:articleTitle |
Polymer-supported tetrafluorophenol: a new activated resin for chemical library synthesis.
|
| pubmed:affiliation |
Lead Discovery Department, Rhone Poulen Rorer, Collegeville, Pennsylvania 19426, USA.
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| pubmed:publicationType |
Journal Article
|