11125352

Source:http://linkedlifedata.com/resource/pubmed/id/11125352

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007634, umls-concept:C0010656, umls-concept:C0033572, umls-concept:C0035820, umls-concept:C0037083, umls-concept:C0162638, umls-concept:C1710082
pubmed:issue	1
pubmed:dateCreated	2001-1-12
pubmed:abstractText	The caspases are an evolutionary conserved family of cell death proteases. Their activation during apoptosis is an important underlying theme in prostate cancer therapy. We summarize the signaling pathways leading to the recruitment of the caspases and address the importance of recent therapeutic strategies aimed at specifically targeting these proteases in relation to prostate cancer.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0376374
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Caspases
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	0022-5347
pubmed:author	pubmed-author:CoffeyR NRN, pubmed-author:FitzpatrickJ MJM, pubmed-author:WatsonR WRW
pubmed:issnType	Print
pubmed:volume	165
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	5-14
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:11125352-Apoptosis, pubmed-meshheading:11125352-Caspases, pubmed-meshheading:11125352-Enzyme Activation, pubmed-meshheading:11125352-Humans, pubmed-meshheading:11125352-Male, pubmed-meshheading:11125352-Prostate, pubmed-meshheading:11125352-Prostatic Neoplasms, pubmed-meshheading:11125352-Signal Transduction
pubmed:year	2001
pubmed:articleTitle	Signaling for the caspases: their role in prostate cell apoptosis.
pubmed:affiliation	Department of Surgery, University College Dublin, Mater Misericordiae Hospital, Dublin, Ireland.
pubmed:publicationType	Journal Article, Review, Research Support, Non-U.S. Gov't