Linked Life Data

11123840

Source:http://linkedlifedata.com/resource/pubmed/id/11123840

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2001-1-26
pubmed:abstractText
Primate molar shapes reflect developmental and ecological processes. Development may constrain as well as facilitate evolution of new tooth shapes, affecting how reliable dental characters are in phylogenetic studies. Much of the genetic machinery of development uses the same genes among different organs, including teeth, limbs, and feathers. Furthermore, within a tooth, the development of individual cusps repeatedly uses the same set of developmental genes, forming a "developmental module." The repeated activation of the developmental module can explain the cumulative variation in later-developing cusps. Therefore short, later-developing cusps may be evolvable but also more homoplastic. This patterning cascade mode of cusp development can be used to explain the variational properties of dental characters and character states related to cusp initiation. The developmental basis and variational properties of crown termination, cusp shape, and cusp configuration characters are currently less well understood. It is unlikely that there is a simple "gene to phenotype" map for dental characters. Rather, the whole cusp pattern is a product of a dynamic developmental program manifested in the activation of the developmental modules.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0002-9483
pubmed:author
pubmed:issnType
Print
pubmed:volume
Suppl 31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
171-90
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Genotype, phenotype, and developmental biology of molar tooth characters.
pubmed:affiliation
Viikki Biocenter, Institute of Biotechnology, University of Helsinki, Helsinki FIN-00014, Finland.
pubmed:publicationType
Journal Article